modulates assembly of the YknX-YknY-YknZ ABC transporter for the export of the SdpC toxin
function
resistence against SdpC toxin
product
modulator of ABC transporter assembly
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|resistance against toxins/ antibiotics], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|AbrB regulon], [SW|SigW regulon]Gene
Coordinates on the chromosome (coding sequence)
1,503,582 -> 1,504,277
The protein
[SW|Localization]
cell membrane (according to Swiss-Prot), membrane [Pubmed|18763711][SW|Interactions]
[protein|search|YknW]-([protein|search|YknX]-([protein|search|YknY]-[protein|search|YknZ]) [Pubmed|22707703]Expression and Regulation
Operon
''[protein|search|yknW]-[protein|search|yknX]-[protein|search|yknY]-[protein|search|yknZ]'' [Pubmed|9987136][SW|Sigma factor]
[protein|search|SigW] [Pubmed|9987136]Regulation
repressed during logrithmic growth ([protein|search|AbrB]) [Pubmed|12076816]Regulatory mechanism
[protein|search|AbrB]: transcription repression [Pubmed|12076816]References
16629676,12076816,18763711,9987136