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tagB

putative CDP-glycerol:glycerol phosphate glycerophosphotransferase

Locus

BSU_35760

Isoelectric point

8.93

Molecular weight

44.40 kDa

Protein length

381 aa Sequence Blast

Gene length

1146 bp Sequence Blast

Function

biosynthesis of teichoic acid

Product

putative CDP-glycerol:glycerol phosphate glycerophosphotransferase

Essential

yes

E.C.

2.7.8.-

Synonyms

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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Categories containing this gene/protein

Cellular processes → Cell envelope and cell division → Cell wall synthesis → Biosynthesis of teichoic acid

Metabolism → Additional metabolic pathways → Biosynthesis of cell wall components → Biosynthesis of teichoic acid

Groups of genes → Essential genes

Groups of genes → Membrane proteins

Gene

Coordinates

3,682,173 3,683,318

Phenotypes of a mutant

essential PubMed

The protein

Catalyzed reaction/ biological activity

adds a single glycerol phosphate residue to the non-reducing end of the undecaprenol-phosphate-linked N-acetylmannosamine-(1,4)-N-acetylglucosamine-1-phosphate PubMed

CDP-glycerol + N-acetyl-β-D-mannosaminyl-(1→4)-N-acetyl-α-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate --> 4-O-[(2R)-glycerylphospho]-N-acetyl-β-D-mannosaminyl-(1→4)-N-acetyl-α-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H⁺ (according to UniProt)

Protein family

CDP-glycerol glycerophosphotransferase family (with TagF, according to UniProt)

Structure

3L7I (from Staphylococcus epidermidis, corresponds to aa 113 ... 380, 31% identity) PubMed

Localization

cell membrane PubMed

Expression and Regulation

Operons

Genes

tagA-tagB

Description

PubMed