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yplP [2019-02-19 20:01:59]
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yplP [2019-02-19 20:01:59]

transcriptional activator (for [protein|1118A21CC581B0470EC6E7C178F2523CDCA70F93|SigL]-dependent promoter)
locus
BSU21780
pI
9.30
mw
37.05 kDa
protein length
331 aa Sequence Blast
gene length
996 bp Sequence Blast
function
required for survival at low temperatures
product
transcriptional activator (for [protein|1118A21CC581B0470EC6E7C178F2523CDCA70F93|SigL]-dependent promoter)
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.5|Cold stress proteins]

    • Gene

    Coordinates
    2,294,286 2,295,281

    Phenotypes of a mutant

  • The mutant is cold-sensitive [http://www.ncbi.nlm.nih.gov/sites/entrez/16585774 PubMed]

    • The protein

    Protein family

  • [SW|Transcription factors activating transcription at SigL-dependent promoters]

    • Structure

  • [PDB|3DZD] (Aquifex aeolicus NtrC, corresponds to aa 12 ... 333 of YplP, 33% identity) [pubmed|18955063]

    • Expression and Regulation

    Operons

    genes
    [gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]-[gene|8C382ECBEE4E2911E0233E0882BEA754156B9D40|yplQ]
    description
    [Pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-A896 (yplP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/896 NBRP B. subtilis, Japan]
  • GP2304 ( ''yplP''::aphA3), available in [SW|Jrg Stlke]'s lab
  • BKE21780 ([gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE21780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATTGGCTCCTTTTGG, downstream forward: _UP4_TAGCGATCGAAAGGAGAATG
  • BKK21780 ([gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK21780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATTGGCTCCTTTTGG, downstream forward: _UP4_TAGCGATCGAAAGGAGAATG

    • References

  • 16585774,12399512,21906631,18955063