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menF
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menF

menaquinone-specific isochorismate synthase
Locus
BSU_30830
Isoelectric point
4.71
Molecular weight
52.65 kDa
Protein length
471 aa Sequence Blast
Gene length
1416 bp Sequence Blast
Function
biosynthesis of menaquinone
Product
menaquinone-specific isochorismate synthase
Essential
no
E.C.
5.4.4.2
Synonyms
icsM,entC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of menaquinone

    • Gene

    Coordinates
    3,152,302 3,153,717

    The protein

    Catalyzed reaction/ biological activity

  • chorismate --> isochorismate (according to UniProt)

    • Protein family

  • isochorismate synthase family (with DhbC, according to UniProt)

    • Structure

  • 3BZM (from Escherichia coli, 33% identity, 51% similarity) PubMed

    • Expression and Regulation

    Operons

    Genes
    menF-menD-ytxM-menB-menE-menC
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Additional information

  • A ncRNA is predicted between 'mntA' and 'menC' PubMed
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    Biological materials

    Mutant

  • BKE30830 (menF::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGAGACATTCCTCCATAA, downstream forward: _UP4_TCTGCATTAGGAGGTGAGAG
  • BKK30830 (menF::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGAGACATTCCTCCATAA, downstream forward: _UP4_TCTGCATTAGGAGGTGAGAG

    • References

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