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fliG [Mon Dec 28 2015 16:28:42 GMT+0100 (CET)]
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fliG [Mon Dec 28 2015 16:28:42 GMT+0100 (CET)]

flagellar basal-body protein, membrane anchor of the basal body, flagellar motor switch protein, physically transduces force from MotA to the rotation of FliF
locus
BSU16220
pI
4.00
mw
38.00 kDa
function
movement and chemotaxis
product
flagellar C ring protein
essential
no
synonyms
flaA15

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.2|Flagellar proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|motility and chemotaxis], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|CodY regulon], [SW|DegU regulon], [SW|SigD regulon], [SW|Spo0A regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,694,119 -> 1,695,135

    Phenotypes of a mutant

  • mucoid phenotype due to the overproduction of poly-gamma-glutamate [Pubmed|24296669]
  • no secretion of [protein|search|FlgM], permanent inhibition of [protein|search|SigD] [Pubmed|25313396]
  • The protein

    Catalyzed reaction/ biological activity

  • physically transduces force from [protein|search|MotA] to the rotation of [protein|search|FliF]
  • Protein family

  • fliG family (according to Swiss-Prot)
  • Effectors of protein activity

  • interaction with [protein|search|EpsE] prevents energetization of the flagellum by [protein|search|MotA]-[protein|search|MotB] [Pubmed|18566286]
  • Structure

  • [PDB|3HJL] (from ''Aquifex aeolicus'', 31% identity)
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|EpsE]-[protein|search|FliG] [Pubmed|18566286]
  • [protein|search|FliF]-[protein|search|FliG] [Pubmed|25313396]
  • [protein|search|FlhG]-([protein|search|FliY]-[protein|search|FliM])-[protein|search|FliG] [Pubmed|25733861]
  • Expression and Regulation

    Operon

  • part of the [[fla-che operon]] (see there for regulation)
  • ''[protein|search|flgB]-[protein|search|flgC]-[protein|search|fliE]-[protein|search|fliF]-[protein|search|fliG]-[protein|search|fliH]-[protein|search|fliI]-[protein|search|fliJ]-[protein|search|ylxF]-[protein|search|fliK]-[protein|search|flgD]-[protein|search|flgE]-[protein|search|fliL]-[protein|search|fliM]-[protein|search|fliY]-[protein|search|cheY]-[protein|search|fliZ]-[protein|search|fliP]-[protein|search|fliQ]-[protein|search|fliR]-[protein|search|flhB]-[protein|search|flhA]-[protein|search|flhF]-[protein|search|flhG]-[protein|search|cheB]-[protein|search|cheA]-[protein|search|cheW]-[protein|search|cheC]-[protein|search|cheD]-[protein|search|sigD]-[protein|search|swrB]'' [Pubmed|9657996,8157612,15175317]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|9657996], [protein|search|SigD] [Pubmed|9657996]
  • Regulation

  • see [[fla-che operon]]
  • Regulatory mechanism

  • see [[fla-che operon]]
  • References

  • 1905667,9657996,8157612,15175317,14651647,18566286,17850253,24296669,25313396,24386445,25733861,26244495