yacO [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

putative 23S rRNA methyltransferase

locus: BSU00960

pI: 8.00

mw: 27.00 kDa

function: unknown

product: putative 23S rRNA methyltransferase

essential: no

ec: 2.1.1.-

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.2|rRNA modification and maturation]

[SW|Categories] containing this gene/protein

• [SW|translation]

This gene is a member of the following [SW|regulons]

• [SW|T-box]

Gene

Coordinates on the chromosome (coding sequence): 115,269 -> 116,018

The protein

Protein family

• RNA methyltransferase trmH family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|YsgA]

Structure

• [PDB|1GZ0] (from ''E. coli'', 44% identity) [Pubmed|12377117]

Expression and Regulation

Operon

• ''[protein|search|gltX]-[protein|search|cysE]-[protein|search|cysS]-[protein|search|mrnC]-[protein|search|yacO]-[protein|search|yacP]'' [Pubmed|7510287]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|7510287]

Regulation

• repression by cysteine ([protein|search|T-box]) [Pubmed|7510287]

Regulatory mechanism

• [protein|search|T-box], overlaps a transcription terminator upstream of ''[protein|search|cysE]'': transcription antitermination [Pubmed|7510287]

References

• 19258532,7510287,12377117