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yvbW
putative leucine permease
product
putative leucine permease
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.4|APC superfamily][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
3,489,910 3,491,253
The protein
Protein family
[SW|amino acid-polyamine-organocation (APC) superfamily] (according to UniProt)Paralogous protein(s)
[protein|9AD0E43119BDC65D5F67CE55CD9417E1E6BAE058|YbxG], [protein|9BFB16C12B31ABD70BBB921BCB9E4201E3BDC92D|RocC], [protein|B46A8BCEC56E6252712E30F8BF8DA6B836FDE2F6|RocE], [protein|B6A920650919D5BBBD75CCA58C30A0D8ECE64DA3|YbgF], [protein|C7FEA1D9C7C96C39CEE83CE3F13D412DE6AFE10E|YdgF], [protein|CE4A49F5CCC2D36C5CE5AD7AE7F0A70F2D4F425C|AapA], [protein|1594BA83CED2DA9F86C1CE2A0DC6E1C9B665EACB|GabP], [protein|219586A3F378DC38EA076FD39B99D41136BDE722|YtnA], [protein|423AEC9D260BE53AD22851D999244B89BEB3E84D|HutM] Structure
[PDB|3GI9] (from ''M. jannaschii'', 23% identity) [Pubmed|19608859][SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|8C4A8961B2514A8AD531AFB104B10C0797D02AC2|yvbW]
description
[pubmed|22383849]
regulatory mechanism
[regulon|T-box|T-box]: anti-termination, in [regulon|T-box|T-box]regulation:
the [SW|T-box] RNA is degraded by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [pubmed|29794222]view in new tabBiological materials
Mutant
GP3038 Δ''[gene|8C4A8961B2514A8AD531AFB104B10C0797D02AC2|yvbW]''::''cat'', available in [SW|Jörg Stülke]'s labMGNA-A468 (yvbW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/468 NBRP B. subtilis, Japan]BKE34010 ([gene|8C4A8961B2514A8AD531AFB104B10C0797D02AC2|yvbW]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE34010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTCTTCTACCTCTCCT, downstream forward: _UP4_TAAATAAGAAACCCTCTTGCBKK34010 ([gene|8C4A8961B2514A8AD531AFB104B10C0797D02AC2|yvbW]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK34010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTCTTCTACCTCTCCT, downstream forward: _UP4_TAAATAAGAAACCCTCTTGCReferences
18625071,19608859,29794222