glucosamine-6-phosphate deaminase
function
glucosamine utilization
product
glucosamine-6-phosphate deaminase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.3|Utilization of cell wall components][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.17|Utilization of amino sugars][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.3|Utilization of amino sugars][SW|Categories] containing this gene/protein
[SW|cell wall degradation/ turnover], [SW|utilization of specific carbon sources]This gene is a member of the following [SW|regulons]
[SW|GamR regulon]Gene
Coordinates on the chromosome (coding sequence)
256,823 -> 257,572
Phenotypes of a mutant
no growth on glucosamine [Pubmed|23667565]The protein
Catalyzed reaction/ biological activity
d-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3 (according to Swiss-Prot)Protein family
NagB subfamily (according to Swiss-Prot)Paralogous protein(s)
[protein|search|NagB]Kinetic information
K(M): 3.0 mM [Pubmed|14343123]Structure
[PDB|2BKX] (the structure of [protein|search|NagB], 50% identity) [Pubmed|15755726]Expression and Regulation
Operon
''[protein|search|gamA]-[protein|search|gamP]'' [Pubmed|23667565][SW|Sigma factor]
[protein|search|SigA] [Pubmed|23667565]Regulation
induced by N-acetylglucosamine [Pubmed|14343123]induced by glucosamine ([protein|search|GamR]) [Pubmed|24673833,23667565]Regulatory mechanism
[protein|search|GamR]: transcription repression [Pubmed|24673833,23667565]References
10627040,14343123,23667565,23876412,24673833,15755726 
