gsaB [2017-8-11 16:0:3]

glutamate-1-semialdehyde aminotransferase

locus: BSU08710

pI: 5.64

mw: 46.04 kDa

protein length: 429 aa

gene length: 1287 bp

function: biosynthesis of heme

product: glutamate-1-semialdehyde aminotransferase

essential: no

ec: 5.4.3.8

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.6|Biosynthesis of heme/ siroheme]
• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.14|Translation factor modification and maturation]
• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.8|Protein modification/ other]

Gene

Coordinates: 942,449 → 943,738

The protein

Catalyzed reaction/ biological activity

• (S)-4-amino-5-oxopentanoate = 5-aminolevulinate (according to Swiss-Prot)

Protein family

• HemL subfamily (according to Swiss-Prot)

Paralogous protein(s)

• [protein|A54B2C86638D474F5F892003B42C535B5B39A42E|HemL]

Structure

• [PDB|3BS8] ([protein|A54B2C86638D474F5F892003B42C535B5B39A42E|HemL]) [Pubmed|20946885]

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|8BB8EECA8ECFA1CC6D46E81250905DBC6D2C503E|gsaB]
  description: [pubmed|22383849]

References

• 20946885