alsR [Mon Aug 31 2015 13:57:09 GMT+0200 (CEST)]

transcriptional activator of the alsS-alsD operon

locus: BSU36020

pI: 7.29

mw: 34.00 kDa

function: regulation of acetoin synthesis (alsS-alsD)

product: transcriptional activator(LysR family)

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.1|Carbon core metabolism] → [category|SW 2.2.1.5|Overflow metabolism]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]

[SW|Categories] containing this gene/protein

• [SW|carbon core metabolism], [SW|transcription factors and their control]

Gene

Phenotypes of a mutant

• no acetoin production

The protein

Catalyzed reaction/ biological activity

• binds the promoter region of the ''[protein|search|alsS]-[protein|search|alsD]'' operon in the presence of acetate, activates transcription

Protein family

• [SW|LysR family] of transcription factors

Biological materials

Mutant

• AMBs3 (spc), available in the [SW|Stülke] lab
• 1A978 ( ''alsR''::''cat''), [Pubmed|7685336], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A978&Search=1A978 BGSC]

Labs working on this gene/protein

• [SW|Elisabeth Härtig], Braunschweig, Germany [http://www.tu-braunschweig.de/ifm/abt/jahn/groups/bs Homepage]

References

Reviews

• 23046954

Original publications

• 7685336,21821766,22344650,23576037,22178965,23695583,23836140