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ytxJ [2019-01-13 20:19:33]
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ytxJ [2019-01-13 20:19:33]

general stress protein, putative bacillredoxin
locus
BSU29760
pI
5.09
mw
12.26 kDa
protein length
108 aa Sequence Blast
gene length
324 bp Sequence Blast
function
unknown
product
putative bacillredoxin
essential
no
synonyms
csb40
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.8|Phosphorylation on either a Ser, Thr or Tyr residue]

    • Gene

    Coordinates
    3,046,757 → 3,047,083

    The protein

    Protein family

  • Trx family

    • [SW|Domains]

  • contains a single conserved Cys residue in a motif (TCPIS) reminiscent of that found in monothiol glutaredoxins [Pubmed|20308541]

    • Modification

  • phosphorylation on (Thr-93 OR Ser-94 OR Ser-96 OR Thr-99) [Pubmed|17218307]

    • Structure

  • [PDB|3IV4] (41% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|00A42FDB559BE2647CD682180420A435E2E7035F|ytxG]-[gene|43BF293F735ED783D36F33AA4701D57F2AED6657|ytxH]-[gene|8B4E1D087B75B5E77BCB60FF3465270CEB72B028|ytxJ]
    description
    [Pubmed|8733232]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|8733232,11544224], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • [protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH]: sigma factor, [Pubmed|8733232], in [regulon|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH regulon]

    • regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|8733232,11544224]
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    Biological materials

    Mutant

  • MGNA-B527 (ytxJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1526 NBRP B. subtilis, Japan]
  • BKE29760 (Δ[gene|8B4E1D087B75B5E77BCB60FF3465270CEB72B028|ytxJ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE29760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTCAAGCTCTTCCTT, downstream forward: _UP4_TAGAAAAAAGCGTCCAGATA
  • BKK29760 (Δ[gene|8B4E1D087B75B5E77BCB60FF3465270CEB72B028|ytxJ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK29760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTCAAGCTCTTCCTT, downstream forward: _UP4_TAGAAAAAAGCGTCCAGATA

    • References

  • 11544224,17218307,8733232,20308541