splA [Mon Aug 31 2015 13:54:00 GMT+0200 (CEST)]

transcriptional repressor of the spore photoproduct lyase splA-splB operon

locus: BSU13920

pI: 4.42

mw: 9.00 kDa

function: regulation of the splA-splB operon

product: transcriptional regulator

essential: no

synonyms: ykxI

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

syns: ykxI

[SW|Categories] containing this gene/protein

• [SW|DNA repair/ recombination], [SW|transcription factors and their control], [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigG regulon]

Expression and Regulation

Operon

• ''[protein|search|splA]-[protein|search|splB]'' [Pubmed|8021181]

[SW|Sigma factor]

• [protein|search|SigG] [Pubmed|15699190,8021181]

Regulation

• expressed during sporulation in the forespore ([protein|search|SigG]) [Pubmed|16497325]

Regulatory mechanism

• negative autoregulation by [protein|search|SplA] [Pubmed|8021181]

References

Reviews

• 23164663

Structure of the spore photoproduct lesion in DNA

• 24598744

Original publications

• 15699190,8021181,22761404,10629212