L-arabinose ABC transporter (integral membrane protein)
function
uptake of arabinose
product
L-arabinose ABC transporter (integral membrane protein))
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.1|Uptake of carbon sources][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.6|Utilization of arabinan/ arabinose/ arabitol][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|utilization of specific carbon sources], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|AraR regulon], [SW|CcpA regulon]Gene
Coordinates on the chromosome (coding sequence)
2,940,697 -> 2,941,638
The protein
Protein family
MalFG subfamily (according to Swiss-Prot)[SW|Localization]
cell membrane [Pubmed|10092453][SW|Interactions]
[protein|search|AraN](2)-([protein|search|AraP]-[protein|search|AraQ])-[protein|search|MsmX] [Pubmed|20693325]Expression and Regulation
Operon
''[protein|search|araA]-[protein|search|araB]-[protein|search|araD]-[protein|search|araL]-[protein|search|araM]-[protein|search|araN]-[protein|search|araP]-[protein|search|araQ]-[protein|search|abfA]'' [Pubmed|9084180][SW|Sigma factor]
[protein|search|SigA] [Pubmed|9084180]Regulation
repressed by glucose ([protein|search|CcpA]) [Pubmed|12949161]induced by arabinose ([protein|search|AraR]) [Pubmed|10417639]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|12949161][protein|search|AraR]: transcription repression [Pubmed|10417639]Additional information
the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]References
12884008,10092453,9084180,10417639,12949161