yfmH

leader peptide to control amino acid-regulated yfmG expression

Locus: new_820648_820823

Isoelectric point: 0.00

Molecular weight: 0.00 kDa

Gene length: 176 bp

Function: control of amino acid-regulated yfmG expression

Product: leader peptide

Synonyms: S254

Genomic Context

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Gene

Coordinates: 820,648 → 820,823

The protein

Catalyzed reaction/ biological activity

• leader peptide PubMed

Expression and Regulation

Operons

• Genes: yfmH-yfmG
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulatory mechanism

  • AbrB: repression, PubMed, in AbrB regulon
  • YfmH: attenuation, PubMed, in YfmH regulon

  Regulation

  • repressed by glucose (4-fold) PubMed

  Additional information

  • A ncRNA is predicted between yfmI and yfmG, this has been shown to encode the leader peptide, YfmH PubMed
  • Expression of yfmG is controlled by YfmH-mediated attenuation: slow translation rates of YfmH due to amino acid limitation prevent the formation in the yfmG leader (reduced expression of yfmG if amino acids are available in excess) PubMed

References

Research papers

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