SubtiBank SubtiBank
yfmH
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yfmH

leader peptide to control amino acid-regulated yfmG expression
Locus
new_820648_820823
Isoelectric point
0.00
Molecular weight
0.00 kDa
Gene length
176 bp Sequence Blast
Function
control of amino acid-regulated yfmG expression
Product
leader peptide
Synonyms
S254

Genomic Context

      
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Gene

Coordinates
820,648 → 820,823

The protein

Catalyzed reaction/ biological activity

  • leader peptide PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • AbrB: repression, PubMed, in AbrB regulon
  • YfmH: attenuation, PubMed, in YfmH regulon
  • Regulation

  • repressed by glucose (4-fold) PubMed
  • Additional information

  • A ncRNA is predicted between yfmI and yfmG, this has been shown to encode the leader peptide, YfmH PubMed
  • Expression of yfmG is controlled by YfmH-mediated attenuation: slow translation rates of YfmH due to amino acid limitation prevent the formation in the yfmG leader (reduced expression of yfmG if amino acids are available in excess) PubMed
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    References

    Research papers

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