yrkQ [2017-8-11 16:0:3]

two-component sensor kinase

locus: BSU26420

pI: 5.16

mw: 49.56 kDa

protein length: 432 aa

gene length: 1296 bp

function: unknown

product: two-component sensor kinase

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]

Gene

Coordinates: 2,703,150 → 2,704,448

The protein

Catalyzed reaction/ biological activity

• autophosphorylation, phosphorylation of [protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|YrkP]

[SW|Domains]

• two transmembrane segments, C-terminal histidine phosphotransferase domain

Modification

• autophosphorylation on a His residue

Expression and Regulation

Operons

• genes: [gene|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]-[gene|8A38FEFAA0FF91D989B77D40CBB3741902DC9D67|yrkQ]-[gene|E0DF6DE230AD0B632EEC0A1FB11EB32E59BD573E|yrkR]
  description: [Pubmed|18175906]

  regulatory mechanism

  • [protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|YrkP]: activation, [Pubmed|18175906], in [regulon|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|YrkP regulon]

Biological materials

Mutant

• MGNA-C423 (yrkQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2421 NBRP B. subtilis, Japan]

References

• 10094672,18175906