yqgP [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

intramembrane protease

locus: BSU24870

pI: 5.51

mw: 56.00 kDa

function: cell division or sugar metabolism

product: intramembrane protease

essential: no

synonyms: glpG, gluP

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|proteolysis], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence): 2,571,907 -> 2,573,430

Phenotypes of a mutant

• filamentous phenotype [Pubmed|15050034]

The protein

Catalyzed reaction/ biological activity

• Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains (according to Swiss-Prot)

Protein family

• peptidase S54 family (according to Swiss-Prot)

[SW|Localization]

• cell membrane [Pubmed|22921757]

[SW|Interactions]

• forms dimers [Pubmed|22921757]

References

Reviews

• 23518036

Original publications

• 19421188,15050034,22921757