tatAC

component of the twin-arginine translocation pathway

locus: BSU_17710

pI: 8.81

mw: 6.71 kDa

protein length: 62 aa

gene length: 189 bp

function: TAT [SW|protein secretion]

product: component of the twin-arginine translocation pathway

essential: no

synonyms: ynzA

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 1,905,370 1,905,558

The protein

Protein family

• TatA/E family (with [protein|E4395255CD43ACB611E0BA872182DF801662C366|TatAD] and [protein|780FDF3DD260287428B397FFE7F44DDF1917381C|TatAY], according to UniProt)

Paralogous protein(s)

• [protein|E4395255CD43ACB611E0BA872182DF801662C366|TatAD], [protein|780FDF3DD260287428B397FFE7F44DDF1917381C|TatAY]

Structure

• [PDB|2L16] ([protein|E4395255CD43ACB611E0BA872182DF801662C366|TatAD], 43% identity) [pubmed|20726548]

[SW|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|8987552EFDF673776741405F7F5FE004556484CA|tatAC]
  description: [Pubmed|22383849]

Biological materials

Mutant

• BKE17710 ([gene|8987552EFDF673776741405F7F5FE004556484CA|tatAC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE17710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCCTTTTCCCCCTGAT, downstream forward: _UP4_TAGGATAAATCGTTTGGGCC
• BKK17710 ([gene|8987552EFDF673776741405F7F5FE004556484CA|tatAC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK17710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCCTTTTCCCCCTGAT, downstream forward: _UP4_TAGGATAAATCGTTTGGGCC

labs

• [SW|Jan Maarten van Dijl], University of Groningen, The Netherlands, [https://www.rug.nl/staff/j.m.van.dijl/ Homepage]

References

Reviews

• 22683878,24140208,25975269,25494301,27121927,31401776

Original publications

• 15554971,22544248,23180473,26239117,20726548