trmD [Sat Oct 08 2016 11:46:29 GMT+0200 (CEST)]

tRNA methyltransferase

locus: BSU16030

pI: 5.00

mw: 27.00 kDa

function: tRNA modification

product: tRNA methyltransferase

essential: yes

ec: 2.1.1.31

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|translation], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence): 1,675,171 -> 1,675,902

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• S-adenosyl-L-methionine tRNA = S-adenosyl-L-homocysteine tRNA containing N(1)-methylguanine (according to Swiss-Prot)

Protein family

• RNA methyltransferase trmD family (according to Swiss-Prot)

Structure

• [PDB|3KY7] (from ''Staphylococcus aureus'', 62% identity)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)