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salA [2017-8-11 16:0:3]
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salA [2017-8-11 16:0:3]

negative regulator of scoC expression, activator of PtkA kinase activity
Locus
BSU01540
Isoelectric point
5.23
Molecular weight
38.48 kDa
Protein length
352 aa Sequence Blast
Gene length
1056 bp Sequence Blast
Function
control of alkaline protease expression
Product
MRP family regulator
Essential
no
Synonyms
ybaL

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
157,421 → 158,479

Phenotypes of a mutant

  • increased expression of aprE (due to loss of repression of scoC expression)
  • The protein

    Catalyzed reaction/ biological activity

  • transcription repression of scoC expression 26094643
  • Protein family

  • Mrp/NBP35 ATP-binding proteins family (according to Swiss-Prot)
  • Domains

  • DNA-binding domain: aa 1 - 60 PubMed
  • ATP-binding Walker domain: aa 105 - 275 PubMed
  • domain for the interaction with PtkA: aa 294 - 352
  • Modification

  • PtkA-dependent phosphorylation at Tyr-327 results in better binding of the target promoter PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Regulatory mechanism

  • SalA: repression, in SalA regulon
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    Biological materials

    Mutant

  • 1A919 ( salA::erm), PubMed, available at BGSC
  • References

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