SubtiBank SubtiBank
tagE [Mon Aug 31 2015 13:57:07 GMT+0200 (CEST)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

tagE [Mon Aug 31 2015 13:57:07 GMT+0200 (CEST)]

UDP-glucose:polyglycerol phosphate glucosyltransferase
locus
BSU35730
pI
6.03
mw
78.00 kDa
function
biosynthesis of teichoic acid
product
UDP-glucose:polyglycerol phosphate glucosyltransferase
essential
no
ec
2.4.1.52
synonyms
rodD, gtaA, gtaD
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.4|Biosynthesis of teichoic acid]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.3|Biosynthesis of teichoic acid]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]
    • syns
    rodD, gtaA, gtaD

    [SW|Categories] containing this gene/protein

  • [SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|phosphoproteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|PhoP regulon], [SW|WalR regulon]

    • Gene

    Phenotypes of a mutant

  • inactivation of ''tagE'' is advantageous in environments with fluctuating glucose availability [Pubmed|23924781]

    • The protein

    Catalyzed reaction/ biological activity

  • transfer of glucose from UDP-glucose to glycerol phosphate in polymeric form [Pubmed|21558268]

    • Protein family

  • glycosyltransferase 1 family (according to Swiss-Prot)

    • Modification

  • phosphorylation on Ser-2 [Pubmed|17218307]

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operon

  • ''[protein|search|tagD]-[protein|search|tagE]-[protein|search|tagF]-[protein|search|tagG]-[protein|search|tagH]'' [Pubmed|22383849]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|7581998]

    • Regulation

  • repressed by phosphate ([protein|search|PhoP]) [Pubmed|9457886]

    • Regulatory mechanism

  • [protein|search|PhoP]: transcription repression [Pubmed|9457886]
  • [protein|search|WalR]: transcription activation [Pubmed|12950927]

    • Biological materials

    Mutant

  • 1A981 ( ''tagE''::''erm''), [Pubmed|18487323], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A981&Search=1A981 BGSC]

    • References

    Reviews

  • 24024634

    • Original publications

  • 9457886,7581998,2507871,17218307,12950927,23924781,21558268,22383849