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capB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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capB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

capsular polyglutamate biosynthesis
Locus
BSU35900
Isoelectric point
5.00
Molecular weight
43.00 kDa
Function
capsule synthesis
Product
poly-gamma-glutamate synthetase
Essential
no
Synonyms
ywsC, pgsB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Cell envelope and cell division → Capsule biosynthesis and degradation

    • Categories containing this gene/protein

  • capsule biosynthesis and degradation

    • This gene is a member of the following regulons

  • DegU regulon

    • Gene

    Coordinates on the chromosome (coding sequence)
    3,699,446 -> 3,700,627

    Phenotypes of a mutant

  • no synthesis of the poly-gamma-glutamate capsule PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • synthesis of poly-gamma-glutamate from L-Glu PubMed

    • Expression and Regulation

    Operon

  • capB-capC-capA-capE PubMed

    • Sigma factor

  • SigA PubMed

    • Regulatory mechanism

  • DegU-P: transcription activation PubMed

    • Additional information

  • The operon is not expressed in the lab strain 168 due to lack of expression of DegQ resulting in inactivity of DegS and DegU PubMed
  • expression of the operon is reduced in 'motA' or 'motB' mutants due to reduced DegU phosphorylation PubMed

    • References

    Reviews

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    Original publications

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