ribC [2019-07-02 08:03:59]

riboflavin kinase / FAD synthase

locus: BSU16670

pI: 8.30

mw: 35.51 kDa

protein length: 316 aa

gene length: 951 bp

function: FAD biosynthesis

product: riboflavin kinase / FAD synthase

essential: yes

ec: 2.7.1.26

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.2|Biosynthesis/ acquisition of riboflavin/ FAD]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

Gene

Coordinates: 1,737,834 1,738,784

Phenotypes of a mutant

• essential [Pubmed|23109554]

The protein

Catalyzed reaction/ biological activity

• ATP + riboflavin = ADP + FMN (according to Swiss-Prot)

Protein family

• ribF family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|3D32B6C1DC9CAC615B02E14EA846648C3B0E61D6|RibR]:

[SW|Cofactors]

• FAD (according to UniProt)

Structure

• [PDB|1S4M] (from ''Thermotoga maritima'', 33% identity, 54% similarity) [Pubmed|15468322]

Expression and Regulation

Operons

• genes: [gene|85E732993186528CF58FECFFE89C8F39D278F28D|ribC]-[gene|EC5D3ECF361C7CDEB606284F5E17243CD926989E|rpsO]
  description: [Pubmed|22383849]

References

• 15468322,23109554,9473052