SubtiBank SubtiBank
pksF [2018-03-02 18:28:10]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

pksF [2018-03-02 18:28:10]

involved in polyketide synthesis
Locus
BSU17140
Isoelectric point
5.37
Molecular weight
44.97 kDa
Protein length
416 aa Sequence Blast
Gene length
1248 bp Sequence Blast
Function
polyketide synthesis
Product
unknown
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
Loading

Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Miscellaneous metabolic pathways → Biosynthesis of antibacterial compounds
  • Lifestyles → Coping with stress → Biosynthesis of antibacterial compounds

    • Gene

    Coordinates
    1,788,695 → 1,789,942

    The protein

    Protein family

  • beta-ketoacyl-ACP synthases family (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    pksC-pksD-pksE-acpK-pksF-pksG-pksH-pksI-pksJ-pksL-pksM-pksN-pksR
    Description
    PubMed

    Regulatory mechanism

  • AbrB: repression, PubMed, in AbrB regulon
  • CodY: activation, PubMed, in CodY regulon

    • Regulation

  • expressed during the transition from growth to stationary phase (AbrB, CodY) PubMed

    • Additional information

  • this is a very large operon comprising about 75 kb
    • view in new tab

    Genes
    pksB-pksC-pksD-pksE-acpK-pksF-pksG-pksH-pksI-pksJ-pksL-pksM-pksN-pksR
    Description
    PubMed
    view in new tab

    Biological materials

    Mutant

  • BKE17140 (ΔpksF::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AACGCCTACACCGGTCACCA, downstream forward: _UP4_GAGAAATGTGGAGGCGAATC
  • BKK17140 (ΔpksF::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AACGCCTACACCGGTCACCA, downstream forward: _UP4_GAGAAATGTGGAGGCGAATC

    • References

    Loading