dipeptide ABC transporter (dipeptide-binding protein)
function
uptake of dipeptides
product
dipeptide ABC transporter (dipeptide-binding protein)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.3|Uptake of peptides][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.4|Utilization of peptides][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|utilization of nitrogen sources other than amino acids], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|CodY regulon]The protein
Protein family
bacterial solute-binding protein 5 family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|OppA][SW|Localization]
attached to the cell membrane (via [protein|search|DppB]-[protein|search|DppC]) [Pubmed|10092453,18763711][SW|Interactions]
([protein|search|DppD]-[protein|search|YkfD])-([protein|search|DppB]-[protein|search|DppC])-[protein|search|DppE] [Pubmed|10092453]Expression and Regulation
Operon
''[protein|search|dppA]-[protein|search|dppB]-[protein|search|dppC]-[protein|search|dppD]-[protein|search|dppE]'' [Pubmed|1766371][SW|Sigma factor]
[protein|search|SigA] [Pubmed|1766371]Regulation
repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|7783641,12618455]Regulatory mechanism
[protein|search|CodY]: transcription repression [Pubmed|7783641,12618455]Biological materials
Mutant
GP1110 (spc), available in [SW|Stülke] lab1A737 ( ''dppE''::''kan''), [Pubmed|1766370], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A737&Search=1A737 BGSC]References
12618455,10092453,1766371,7783641,1766371,18763711 
