protein serine phosphatase, feedback PP2C, dephosphorylates RsbS and RsbR
function
control of SigB activity
product
protein serine phosphatase, feedback PP2C
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.4|Protein phosphatases][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)][SW|Categories] containing this gene/protein
[SW|protein modification], [SW|sigma factors and their control], [SW|general stress proteins (controlled by SigB)]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|SigB regulon]The protein
Catalyzed reaction/ biological activity
dephosphorylation of [protein|search|RsbR]-P [Pubmed|15466036] and [protein|search|RsbS]-S59-P [Pubmed|8824586,21362065]Structure
[PDB|3W42], [PDB|3W43] [Pubmed|26057679][SW|Interactions]
[protein|search|RsbX]-[protein|search|RsbR] [Pubmed|15466036][protein|search|RsbX]-[protein|search|RsbS] [Pubmed|8824586]Expression and Regulation
Operon
''[protein|search|rsbR]-[protein|search|rsbS]-[protein|search|rsbT]-[protein|search|rsbU]-[protein|search|rsbV]-[protein|search|rsbW]-[protein|search|sigB]-[protein|search|rsbX]'' [Pubmed|8002610]''[protein|search|rsbV]-[protein|search|rsbW]-[protein|search|sigB]-[protein|search|rsbX]'' [Pubmed|2170324][SW|Sigma factor]
''[protein|search|rsbR]'': [protein|search|SigA] [Pubmed|8002610]''[protein|search|rsbV]:'' [protein|search|SigB] [Pubmed|11544224]Regulation
''[protein|search|rsbV]:'' induced by stress ([protein|search|SigB]) [Pubmed|11544224]Labs working on this gene/protein
[SW|Bill Haldenwang], San Antonio, USA[SW|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]References
8002610,8682769,9658013,8002609,10671474,9068644,19923733,11544224,15466036,8824586,23407164,23320651,21362065,26057679 
