lctP [Mon Aug 31 2015 13:52:15 GMT+0200 (CEST)]

lactate permease, excretion

locus: BSU03060

pI: 9.77

mw: 57.00 kDa

function: lactate excretion

product: L-lactate permease

essential: no

synonyms: ycgC

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.4|Transporter for organic acids]
• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.1|Carbon core metabolism] → [category|SW 2.2.1.5|Overflow metabolism]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

syns: ycgC

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|carbon core metabolism], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|Rex regulon]

The protein

Protein family

• lactate permease family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|LutP]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|ldh]-[protein|search|lctP]'' [Pubmed|16207915]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|10809684]

Regulation

• induced under anaerobic conditions ([protein|search|Rex]) [Pubmed|16207915]

Regulatory mechanism

• [protein|search|Rex]: transcription repression [Pubmed|16207915]

References

• 16207915,10809684,16428414,17573341