sknR [Mon Aug 31 2015 13:55:48 GMT+0200 (CEST)]

transcriptional repressor (Xre family) of the yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqaN operon of the skin element (Xre family)

locus: BSU26350

pI: 5.42

mw: 13.00 kDa

function: control of prophage gene expression

product: transcriptional repressor (Xre family)

essential: yes

synonyms: yqaE

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.3|Skin element]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

syns: yqaE

[SW|Categories] containing this gene/protein

• [SW|transcription factors and their control], [SW|Skin element], [SW|essential genes]

Gene

Phenotypes of a mutant

• essential in the wild type background (due to overexpression of the toxic proteins [protein|search|YqaH] and [protein|search|YqaM]) [Pubmed|20889742]
• no phenotype if deleted with the complete [SW|skin element] [Pubmed|20889742]

The protein

Catalyzed reaction/ biological activity

• binds the yqaF promoter region to repress transcription of the ''[protein|search|yqaF]-[protein|search|yqdA]-[protein|search|yqaG]-[protein|search|yqaH]-[protein|search|yqaI]-[protein|search|yqaJ]-[protein|search|yqaK]-[protein|search|yqaL]-[protein|search|yqaM]-[protein|search|yqzO]-[protein|search|yqaN]'' operon [Pubmed|20889742]

Protein family

• [SW|Xre family]

Paralogous protein(s)

• [protein|search|YonR], [protein|search|Xre]

References

• 20889742