gpsA [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

glycerol-3-phosphate dehydrogenase (NAD)

locus: BSU22830

pI: 6.23

mw: 37.00 kDa

function: biosynthesis of phospholipids

product: glycerol-3-phosphate dehydrogenase (NAD)

essential: yes

ec: 1.1.1.94

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.2|Biosynthesis of phospholipids]
• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.9|Newly identified competence genes]
• [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation] → [category|SW 4.1.2.5|Other proteins required for biofilm formation]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis of lipids], [SW|essential genes]

Gene

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• sn-glycerol 3-phosphate + NAD(P)⁺ = glycerone phosphate + NAD(P)H (according to Swiss-Prot)

Protein family

• NAD-dependent glycerol-3-phosphate dehydrogenase family (according to Swiss-Prot)

Structure

• [PDB|3K96] (from ''Coxiella burnetii RSA 493'', 37% identity, 59% similarity)

[SW|Localization]

• cytoplasm [Pubmed|15743965]

References

• 7592341,15743965