prkA [Sun May 08 2016 12:10:45 GMT+0200 (CEST)]

putative serine protein kinase

locus: BSU08970

pI: 5.00

mw: 72.00 kDa

function: control of SigK-dependent gene expression

product: putative serine protein kinase

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

[SW|Categories] containing this gene/protein

• [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigE regulon]

Gene

Coordinates on the chromosome (coding sequence): 973,156 -> 975,051

Phenotypes of a mutant

• sporulation frequency reduced to 12-27% in knockout [Pubmed|12662922], due to reduced [SW|SigK] expression, results from strong repression by [SW|ScoC] [Pubmed|25983726]

The protein

Catalyzed reaction/ biological activity

• inactivation of [SW|ScoC] [Pubmed|25983726]

Protein family

• prkA family (according to Swiss-Prot)

[SW|Localization]

• spore coat [Pubmed|25983726]

Additional information

• [http://ecocyc.org/ECOLI/NEW-IMAGE?type=ENZYME&object=G6969-MONOMER the corresponding protein from ''E. coli'' (YeaG)]

Expression and Regulation

Operon

• ''prkA'' [Pubmed|8626065]

[SW|Sigma factor]

• [protein|search|SigE] [Pubmed|15699190,12662922]

Regulation

• repressed by casamino acids [Pubmed|12107147]

References

• 12662922,18276156,12107147,8626065,25983726