membrane-bound chemotaxis receptor for proline, methyl-accepting chemotaxis protein
function
control of chemotaxis
threonine, glycine, serine, lysine, valine and arginine
product
methyl-accepting chemotaxis protein
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.1|Signal transduction in motility and chemotaxis] → [category|SW 4.1.1.1.4|Membrane-bound chemoreceptors][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|motility and chemotaxis], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigD regulon]Gene
Coordinates on the chromosome (coding sequence)
1,463,628 -> 1,465,595
The protein
Catalyzed reaction/ biological activity
deaminated [protein|search|McpC] stimulates phosphorylation of [protein|search|CheA] [Pubmed|22931217]Modification
deamination of Gln-609 (by [protein|search|CheD]) [Pubmed|22931217], deaminated [protein|search|McpC] stimulates phosphorylation of [protein|search|CheA] [Pubmed|22931217][SW|Localization]
cell membrane [Pubmed|18763711,21515776][SW|Interactions]
[protein|search|CheD]-[protein|search|McpC], deamination of Gln-609 in [protein|search|McpC] [Pubmed|22931217][protein|search|McpC]-[protein|search|ArtP], for chemotaxis to lysine and arginine [Pubmed|23038252][protein|search|McpC]-[protein|search|MetQ], for chemotaxis to methionine [Pubmed|23038252][protein|search|McpC]-[protein|search|YckB], for chemotaxis to tryptophan [Pubmed|23038252]Expression and Regulation
Operon
''[protein|search|mcpC]'' [Pubmed|9353924][SW|Sigma factor]
[protein|search|SigD] [Pubmed|9353924]Additional information
in minimal medium, McpC is present with 2,800 /- 640 molecules per cell [PubMed|21515776] Biological materials
Mutant
DS180 (''mcpC''::''mls'' in NCIB3610) [Pubmed|12864845]References
12864845,15317802,8251536,9353924,15544802,6137212,9721285,2505839,2105313,12603740,23038252,18763711,9721285,21515776,22931217 
