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argB [Mon May 16 2016 17:03:13 GMT+0200 (CEST)]
N-acetylglutamate 5-phosphotransferase
function
biosynthesis of arginine
product
N-acetylglutamate 5-phosphotransferase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.4|Biosynthesis/ acquisition of arginine][SW|Categories] containing this gene/protein
[SW|biosynthesis/ acquisition of amino acids]This gene is a member of the following [SW|regulons]
[SW|AhrC regulon], [SW|CodY regulon]Gene
Coordinates on the chromosome (coding sequence)
1,197,326 -> 1,198,102
The protein
Catalyzed reaction/ biological activity
ATP N-acetyl-L-glutamate = ADP N-acetyl-L-glutamate 5-phosphate (according to Swiss-Prot) Protein family
acetylglutamate kinase family (according to Swiss-Prot)[SW|Localization]
cytoplasm (according to Swiss-Prot)Additional information
:subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17981983 PubMed] Expression and Regulation
Operon
''[protein|search|argC]-[protein|search|argJ]-[protein|search|argB]-[protein|search|argD]-[protein|search|carA]-[protein|search|carB]-[protein|search|argF]'' [Pubmed|7511775][SW|Sigma factor]
[protein|search|SigA] [Pubmed|7511775]Regulation
repressed by casamino acids ([protein|search|CodY]) [Pubmed|12107147]repressed by arginine ([protein|search|AhrC]) [Pubmed|1312212]Regulatory mechanism
[protein|search|AhrC]: transcription repression [Pubmed|1312212][protein|search|CodY]: transcription repression [Pubmed|24843172]Additional information
subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17981983 PubMed] References
6096675,24843172,12107147 
