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serS [Mon Aug 31 2015 13:51:45 GMT+0200 (CEST)]
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serS [Mon Aug 31 2015 13:51:45 GMT+0200 (CEST)]

seryl-tRNA-synthetase
locus
BSU00130
pI
5.19
mw
48.00 kDa
function
translation
product
seryl-tRNA-synthetase
essential
yes
ec
6.1.1.11
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.10|Aminoacyl-tRNA synthetases]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

    • [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|essential genes]

    • This gene is a member of the following [SW|regulons]

  • [SW|T-box]

    • Gene

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Catalyzed reaction/ biological activity

  • ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser) (according to Swiss-Prot)

    • Protein family

  • Type-1 seryl-tRNA synthetase subfamily (according to Swiss-Prot)

    • Structure

  • [PDB|1SES] (from ''Thermus thermophilus'', 36% identity, 56% similarity) [Pubmed|8128224]

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operon

  • ''serS'' [Pubmed|8915527]

    • Regulation

  • induced by serine limitation ([protein|search|T-box]) [Pubmed|19258532]

    • Regulatory mechanism

  • [protein|search|T-box]: [SW|RNA switch], transcriptional antitermination [Pubmed|19258532]

    • References

  • 19258532,8915527