sigZ [2019-04-14 15:47:44]

[SW|RNA polymerase] ECF-type [SW|sigma factor] SigZ

locus: BSU26840

pI: 6.24

mw: 20.57 kDa

protein length: 176 aa

gene length: 531 bp

function: [category|SW 3.2.1|Transcription]

product: [SW|RNA polymerase] ECF-type [SW|sigma factor] SigZ

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors]

Gene

Coordinates: 2,742,244 2,742,774

The protein

Protein family

• [SW|Sigma-70 factor family] (according to UniProt)
• ECF subfamily (according to Swiss-Prot)

Structure

• [PDB|5WUQ] ([protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW], 29% identity) [pubmed|28319136]

Biological materials

Mutant

• MGNA-A143 (sigZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/143 NBRP B. subtilis, Japan]
• 1A902 ( ''sigZ''::''kan''), [Pubmed|15838020], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A902&Search=1A902 BGSC]
• BKE26840 ([gene|826F81933BE84AEF0C71EE9B90390B14B4CB0E9F|sigZ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE26840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGAAAAAACCTCCTAT, downstream forward: _UP4_TAACTGATGAACATAGTCAG
• BKK26840 ([gene|826F81933BE84AEF0C71EE9B90390B14B4CB0E9F|sigZ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK26840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGAAAAAACCTCCTAT, downstream forward: _UP4_TAACTGATGAACATAGTCAG

References

Reviews

• 24921931

Original publications

• 17675383,20817771,27137497,28319136