outer spore coat morphogenetic protein, controls the assembly of the outer spore coat layer
function
assembly of the outer spore coat
product
spore coat morphogenetic protein
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.2|Class II][SW|Categories] containing this gene/protein
[SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|SigE regulon], [SW|SigK regulon], [SW|GerE regulon]Gene
Coordinates on the chromosome (coding sequence)
1,775,067 -> 1,775,612
Phenotypes of a mutant
mis-assembly of the outer spore coat [Pubmed|22171814]inactivation of ''[SW|cotE]'' reduces sporulation efficiency to 49.1% that of wild type cells [Pubmed|26735940]The protein
Catalyzed reaction/ biological activity
assembly of the [protein|search|CotC]-[protein|search|CotU] complex [Pubmed|20023017,18065538]Protein family
cotE family (according to Swiss-Prot)[SW|Localization]
encircles the forespore with a biased accumulation on the mother cell-proximal face of the forespore [Pubmed|23267091,22463703]outer spore coat, localization depends on [SW|SpoIVA] [Pubmed|22773792,22171814][SW|Interactions]
homotypic interaction [Pubmed|19304857][protein|search|CotE]-[protein|search|CotC] [Pubmed|20023017][protein|search|CotE]-[protein|search|CotU] [Pubmed|20023017][SW|SpoVID]-[protein|search|CotE] [Pubmed|23178679,22773792][protein|search|CotE]-[protein|search|CotH] [Pubmed|26484546][protein|search|CotE]-[protein|search|CotX] [Pubmed|26821119][protein|search|CotE]-[protein|search|CotY] [Pubmed|26821119]Expression and Regulation
Operon
''[protein|search|cotE]'' [Pubmed|8760914][SW|Sigma factor]
[protein|search|SigE] [Pubmed|15699190,1691789], [protein|search|SigK] [Pubmed|1691789]Regulation
repressed by casamino acids [Pubmed|12107147]expressed during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE]) [Pubmed|1691789,15383836]Regulatory mechanism
[protein|search|GerE]: transcription repression [Pubmed|15383836]Biological materials
Mutant
1S105 ( ''cotE''::''cat''), [Pubmed|3139490], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S105&Search=1S105 BGSC]Labs working on this gene/protein
[SW|Arthur Aronson], Purdue University, West Lafayette, USA [http://wwwdev.gradschool.purdue.edu/PULSe/faculty.cfm?fid=5&range=0 homepage][SW|Adriano Henriques], Lisbon, Portugal [http://www.itqb.unl.pt/research/biology/microbial-development homepage]References
Reviews
22192522,23202530,27227299 Original publications
8748030,17720779,10559171,8760914,15699190,7592342,3139490,8299942,1691789,12644503,17172339,19304857,11737650,12107147,20023017,18065538,22773792,15383836,22171814,23064347,23178679,23267091,22463703,21821751,24086406,25259857,25872412,26484546,26821119,26735940 
