dra [2017-8-11 16:0:3]

deoxyribose-phosphate aldolase

locus: BSU39420

pI: 4.93

mw: 22.06 kDa

protein length: 211 aa

gene length: 633 bp

function: utilization of nucleotides as carbon source

product: deoxyribose-phosphate aldolase

essential: no

ec: 4.1.2.4

synonyms: deoC

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.1|Utilization of nucleotides]

Gene

Coordinates: 4,051,602 → 4,052,273

The protein

Catalyzed reaction/ biological activity

• 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde (according to Swiss-Prot)

Protein family

• DeoC type 1 subfamily (according to Swiss-Prot)

Structure

• [PDB|1MZH] (from ''Aquifex aeolicus'', 42% identity, 62% similarity)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|81CD1F97E887549F7FB742FCEF38B86B84383F5D|dra]-[gene|4F718681A7AD0C86B2551248570F493AC0B2E7E9|nupC]-[gene|D2EB7BBAC8817912DAC4E215879F5A4E2C47ECAF|pdp]
  description: [Pubmed|8550462]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|8550462], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

  regulatory mechanism

  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|10666464], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]
  • [protein|E9C4C569F18B3335DA9C7FB5B17C87D661E62669|DeoR]: repression, [Pubmed|8550462], in [regulon|E9C4C569F18B3335DA9C7FB5B17C87D661E62669|DeoR regulon]

  regulation

  • induced by deoxynucleotides ([protein|search|DeoR]) [Pubmed|8550462]

References

• 10666464,11065368,8550462,10074062