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flgD [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]
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flgD [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

flagellar hook cap, required for hook assembly
locus
BSU16280
pI
4.00
mw
15.00 kDa
function
flagellar hook assembly
product
flagellar hook cap
essential
no
synonyms
ylxG

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.2|Flagellar proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|motility and chemotaxis]
  • This gene is a member of the following [SW|regulons]

  • [SW|CodY regulon], [SW|DegU regulon], [SW|SigD regulon], [SW|Spo0A regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,699,738 -> 1,700,160

    Phenotypes of a mutant

  • lack of [protein|search|SigD]-dependent gene expression (no ''[protein|search|hag]'' expression), no motility [Pubmed|22730131]
  • The protein

    Catalyzed reaction/ biological activity

  • flagellar hook assembly [Pubmed|22730131]
  • assists incorporation of a [SW|FlgE] monomer into the nascent hook structure [Pubmed|26490009]
  • Protein family

  • flgD family (according to Swiss-Prot)
  • [SW|Interactions]

  • [SW|FlgD]-[SW|FlgE] [Pubmed|26490009]
  • Expression and Regulation

    Operon

  • part of the [[fla-che operon]] (see there for regulation)
  • ''[protein|search|flgB]-[protein|search|flgC]-[protein|search|fliE]-[protein|search|fliF]-[protein|search|fliG]-[protein|search|fliH]-[protein|search|fliI]-[protein|search|fliJ]-[protein|search|ylxF]-[protein|search|fliK]-[protein|search|flgD]-[protein|search|flgE]-[protein|search|fliL]-[protein|search|fliM]-[protein|search|fliY]-[protein|search|cheY]-[protein|search|fliZ]-[protein|search|fliP]-[protein|search|fliQ]-[protein|search|fliR]-[protein|search|flhB]-[protein|search|flhA]-[protein|search|flhF]-[protein|search|flhG]-[protein|search|cheB]-[protein|search|cheA]-[protein|search|cheW]-[protein|search|cheC]-[protein|search|cheD]-[protein|search|sigD]-[protein|search|swrB]'' [Pubmed|9657996,8157612,15175317]
  • ''[protein|search|ylxF]-[protein|search|fliK]-[protein|search|flgD]-[protein|search|flgE]-[protein|search|fliL]-[protein|search|fliM]-[protein|search|fliY]-[protein|search|cheY]-[protein|search|fliZ]-[protein|search|fliP]-[protein|search|fliQ]-[protein|search|fliR]-[protein|search|flhB]-[protein|search|flhA]-[protein|search|flhF]-[protein|search|flhG]-[protein|search|cheB]-[protein|search|cheA]-[protein|search|cheW]-[protein|search|cheC]-[protein|search|cheD]-[protein|search|sigD]-[protein|search|swrB]'' [Pubmed|20233303]
  • [SW|Sigma factor]

  • ''[protein|search|flgB]'': [protein|search|SigA] [Pubmed|9657996], [protein|search|SigD] [Pubmed|9657996]
  • ''[protein|search|ylxF]'': [protein|search|SigD] [Pubmed|20233303]
  • Regulation

  • see [[fla-che operon]]
  • Regulatory mechanism

  • see [[fla-che operon]]
  • Biological materials

    Mutant

  • MGNA-B104 (ylxG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1103 NBRP B. subtilis, Japan]
  • References

    Reviews

  • 26490009
  • Original publications

  • 14651647,9657996,8157612,15175317,17850253,22730131,24386445