SubtiBank SubtiBank
dtpT
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dtpT

proton-dependent di- and tripeptide transporter
Locus
BSU_03670
Isoelectric point
9.92
Molecular weight
53.11 kDa
Protein length
492 aa Sequence Blast
Gene length
1479 bp Sequence Blast
Function
uptake of di- and tripeptides
Product
peptide transporter
Essential
no
Synonyms
yclF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Transporters → Transporters/ other → Peptide transporter
  • Metabolism → Amino acid/ nitrogen metabolism → Utilization of nitrogen sources other than amino acids → Utilization of peptides
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    416,235 417,713

    The protein

    Protein family

  • PTR2/POT transporter (TC 2.A.17) family (single member, according to UniProt)

    • Structure

  • 4IKV, the protein from Geobacillus kaustophilus (65% identity, 87% similarity), PubMed

    • Localization

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    Genes
    dtpT
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • ScoC: repression, PubMed, in ScoC regulon
  • TnrA: activation, in TnrA regulon

    • Regulation

  • repressed during exponential growth (ScoC) PubMed
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    Additional information

  • the mRNA is cleaved by RNase III PubMed

    • Biological materials

    Mutant

  • BKE03670 (dtpT::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTCAGCCAAACCCTTTC, downstream forward: _UP4_TAATCAGAAACAGCCCGCGG
  • BKK03670 (dtpT::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTCAGCCAAACCCTTTC, downstream forward: _UP4_TAATCAGAAACAGCCCGCGG

    • References

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