yfiZ

ABC transporter for the siderophore schizokinen and arthrobactin (permease), works with ATPase YusV

Locus: BSU_08450

Isoelectric point: 9.62

Molecular weight: 34.98 kDa

Protein length: 333 aa

Gene length: 1002 bp

Function: acquisition of iron

Product: ABC transporter for the siderophore schizokinen and arthrobactin (permease)

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → ABC transporters → Importers → Uptake of iron/ siderophores
• Cellular processes → Homeostasis → Acquisition of iron → ABC transporters for the uptake of iron/ siderophores
• Metabolism → Additional metabolic pathways → Iron metabolism → ABC transporters for the uptake of iron/ siderophores
• Groups of genes → Membrane proteins

Gene

Coordinates: 920,474 921,475

The protein

Protein family

• Binding-protein-dependent transport system permease family (according to UniProt)
• FecCD subfamily (according to UniProt)

Paralogous protein(s)

• FecD, FhuB

Structure

• 2NQ2 (complex with YusV-like protein, from Haemophilus influenzae, 33% identity) PubMed

Localization

• cell membrane PubMed

Expression and Regulation

Operons

• Genes: yfiZ-yfhA
  Description: PubMed

  Regulatory mechanism

  • Fur: repression, PubMed, in Fur regulon

Biological materials

Mutant

• MGNA-C312 (yfiZ::erm), available at the NBRP B. subtilis, Japan
• BKE08450 (yfiZ::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGATCTAATTCTCCTAGT, downstream forward: _UP4_CTATGAAACTTCGTTTTGGC
• BKK08450 (yfiZ::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGATCTAATTCTCCTAGT, downstream forward: _UP4_CTATGAAACTTCGTTTTGGC

References

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