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rplT [Fri Jan 29 2016 16:57:41 GMT+0100 (CET)]
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rplT [Fri Jan 29 2016 16:57:41 GMT+0100 (CET)]

ribosomal protein
locus
BSU28850
pI
11.00
mw
13.00 kDa
function
translation
product
ribosomal protein L20
essential
yes
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.4|RNA binding regulators]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|RNA binding regulators], [SW|essential genes], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|RplT regulon], [SW|stringent response]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,952,224 -> 2,952,583

    Phenotypes of a mutant

  • essential [Pubmed|23002217,12682299]
  • The protein

    Protein family

  • [SW|ribosomal protein] L20P family (according to Swiss-Prot)
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|infC]-[protein|search|rpmI]-[protein|search|rplT]-[protein|search|ysdA]'' [Pubmed|17289755]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|17289755]
  • Regulation

  • [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • Regulatory mechanism

  • binding of [protein|search|RplT] to a [SW|RNA switch] in the ''[protein|search|infC]'' leader region causes transcription termination [Pubmed|17289755]
  • Additional information

  • expression of [infC|search|IF3] is uncoupled from that of [rpmI|search|L35] and [rplT|search|L20] by [rny|search|RNase Y]-dependent processing [PubMed|21843271]
  • References

  • 19653700,11948165,17289755,21843271,23002217,23611891