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pnbA [Mon Aug 31 2015 13:56:56 GMT+0200 (CEST)]
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pnbA [Mon Aug 31 2015 13:56:56 GMT+0200 (CEST)]

para-nitrobenzyl esterase
locus
BSU34390
pI
4.78
mw
53.00 kDa
function
lipid degradation
product
para-nitrobenzyl esterase
essential
no
ec
3.1.1.3
synonyms
estB

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.1|Utilization of lipids] → [category|SW 2.4.1.4|Utilization of lipids/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]
  • syns
    estB

    [SW|Categories] containing this gene/protein

  • [SW|utilization of lipids], [SW|phosphoproteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • Triacylglycerol + H2O = diacylglycerol + a carboxylate (according to Swiss-Prot)
  • Protein family

  • type-B carboxylesterase/lipase family (according to Swiss-Prot)
  • Modification

  • phosphorylation on Ser-189 [Pubmed|17218307]
  • Structure

  • [PDB|1C7J] [Pubmed|10535917]
  • Expression and Regulation

    Regulation

  • repressed during logarithmic growth ([protein|search|AbrB]) [Pubmed|18840696]
  • Regulatory mechanism

  • [protein|search|AbrB]: transcription repression [Pubmed|18840696]
  • Biological materials

    Mutant

  • GP951 (''pnbA''::''cat''), available in [SW|Jörg Stülke]'s lab
  • GP955 (''[protein|search|slrR]''-''pnbA''::''cat''), available in [SW|Jörg Stülke]'s lab
  • References

  • 7828905,21574267,17218307,10535917,22127613,25077141