czcD [Mon Aug 31 2015 13:55:50 GMT+0200 (CEST)]

cation diffusion facilitator

locus: BSU26650

pI: 5.86

mw: 34.00 kDa

function: cation efflux, resistence against Zn, Cu, Co, Ni

product: cation diffusion facilitator

essential: no

synonyms: yrdO

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.5|Metal ion transporter]
• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.2|Trace metal homeostasis (Cu, Zn, Ni, Mn, Mo)] → [category|SW 1.3.2.3|Zinc]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.11|Resistance against toxic metals]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

syns: yrdO

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|trace metal homeostasis (Cu, Zn, Ni, Mn, Mo)], [SW|resistance against toxic metals], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|CzrA regulon]

The protein

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|czcD]-[protein|search|trkA]'' [Pubmed|15948947]

Regulation

• induced in the presence of toxic metal ions (Zn(II), Cd(II), Co(II), Ni(II) and Cu(II)) ([protein|search|CzrA]) [Pubmed|15948947]

Regulatory mechanism

• [protein|search|CzrA]: transcription repression [Pubmed|15948947]

References

• 15948947