rpmI [Fri Jan 29 2016 17:14:29 GMT+0100 (CET)]

ribosomal protein

locus: BSU28860

pI: 12.00

mw: 7.00 kDa

function: translation

product: ribosomal protein L35

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins]

[SW|Categories] containing this gene/protein

• [SW|translation]

This gene is a member of the following [SW|regulons]

• [SW|RplT regulon], [SW|stringent response]

Gene

Coordinates on the chromosome (coding sequence): 2,952,615 -> 2,952,815

The protein

Protein family

• [SW|ribosomal protein] L35P family (according to Swiss-Prot)

Additional information

• the protein is significantly underrepresented in 45S assembly intermediates that accumulate upon depletion of [protein|search|RbgA] [Pubmed|24335279,23700310]

Expression and Regulation

Operon

• ''[protein|search|infC]-[protein|search|rpmI]-[protein|search|rplT]-[protein|search|ysdA]'' [Pubmed|17289755]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|17289755]

Regulation

• [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]

Regulatory mechanism

• binding of [protein|search|RplT] to a [SW|RNA switch] in the ''[protein|search|infC]'' leader region causes transcription termination [Pubmed|17289755]

Additional information

• expression of [infC|search|IF3] is uncoupled from that of [rpmI|search|L35] and [rplT|search|L20] by [rny|search|RNase Y]-dependent processing [PubMed|21843271]

References

• 19653700,17289755,11948165,21843271,23002217,24335279,23700310