yvmA [2019-06-12 10:22:58]

similar to multidrug transporter

locus: BSU35090

pI: 9.69

mw: 43.10 kDa

protein length: 403 aa

gene length: 1212 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 3,605,523 3,606,734

The protein

Protein family

• [SW|major facilitator superfamily] (according to UniProt)
• TCR/tet family (according to Swiss-Prot)

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|0D555F2AB7DC863E6FF388888308E980514DB719|pchR]-[gene|7F10DEEDEF8B679F4F2C5EAD5752F4E399DB0D57|yvmA]
  description: [Pubmed|22383849]

  regulatory mechanism

  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|12850135]; [protein|0D555F2AB7DC863E6FF388888308E980514DB719|PchR] auto-repression [Pubmed|27542896], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]
  • [protein|0D555F2AB7DC863E6FF388888308E980514DB719|PchR]: repression, in [regulon|0D555F2AB7DC863E6FF388888308E980514DB719|PchR regulon]

  regulation

  • induced by iron starvation [Pubmed|27542896]

Biological materials

Mutant

• BKE35090 ([gene|7F10DEEDEF8B679F4F2C5EAD5752F4E399DB0D57|yvmA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE35090 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGTGTACACCGCCTTTT, downstream forward: _UP4_TAAAAAAGCTGCCTTTGCGG
• BKK35090 ([gene|7F10DEEDEF8B679F4F2C5EAD5752F4E399DB0D57|yvmA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK35090 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGTGTACACCGCCTTTT, downstream forward: _UP4_TAAAAAAGCTGCCTTTGCGG

References

• 22383849,27542896