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yodF [2020-08-11 09:46:13]
similar to amino acid permease
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.1|Solute:sodium symporter family][category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.7|Sodium-solute symporter][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.4|Putative amino acid transporter][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
2,130,377 2,131,867
The protein
Catalyzed reaction/ biological activity
in some database, the protein is annotated as being similar to proline permease, however, it is not involved in proline transport [Pubmed|24142252]Protein family
[SW|sodium:solute symporter (SSF) (TC 2.A.21) family] (according to UniProt)Paralogous protein(s)
[protein|EFA18ACD034D48868CD97470F81F23976DA300DF|YhjB] [SW|Localization]
membrane [Pubmed|18763711]Expression and Regulation
Operons
genes
[gene|80D8589800BC9BA6743534311B6F227A37E7DB2D|yoyD]-[gene|7E86EB6FF86F2C4AE3FD11DB8CE8E71696D94B1B|yodF]
description
[Pubmed|22383849]
regulatory mechanism
[protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA]: repression, [Pubmed|25755103,12823818], in [regulon|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA regulon]regulation
expression during spore [SW|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]view in new tabBiological materials
Mutant
MGNA-B437 (yodF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1436 NBRP B. subtilis, Japan]available in [SW|Erhard Bremer]'s lab [Pubmed|24142252]GP1887 Δ[gene|7E86EB6FF86F2C4AE3FD11DB8CE8E71696D94B1B|yodF]::kan, available in [SW|Jörg Stülke]'s labBKE19580 ([gene|7E86EB6FF86F2C4AE3FD11DB8CE8E71696D94B1B|yodF]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE19580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAGTGCAGTCAGATTCCCTT, downstream forward: _UP4_TAAAAAAACCATACGCGGCABKK19580 ([gene|7E86EB6FF86F2C4AE3FD11DB8CE8E71696D94B1B|yodF]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK19580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAGTGCAGTCAGATTCCCTT, downstream forward: _UP4_TAAAAAAACCATACGCGGCAReferences
12823818,22383849,12107147,18763711,24142252,25755103