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cdsA [2019-07-02 08:02:26]
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cdsA [2019-07-02 08:02:26]

phosphatidate cytidylyltransferase
locus
BSU16540
pI
7.87
mw
30.06 kDa
protein length
269 aa Sequence Blast
gene length
810 bp Sequence Blast
function
biosynthesis of phospholipids
product
phosphatidate cytidylyltransferase
essential
yes
ec
2.7.7.41
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.2|Biosynthesis of phospholipids]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,722,000 1,722,809

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Catalyzed reaction/ biological activity

  • CTP + phosphatidate = diphosphate + CDP-diacylglycerol (according to Swiss-Prot)

    • Protein family

  • CDS family (according to Swiss-Prot)

    • Structure

  • [PDB|4Q2G] (from ''Thermotoga maritima'', 36% identity) [Pubmed|24968740]

    • [SW|Localization]

  • cell membrane at the septum [Pubmed|15743965,19820159]

    • Expression and Regulation

    Operons

    genes
    [gene|4A637EB9B400D30E5C6246D1E0EB5E6A30F38A16|uppS]-[gene|7E7F6BBA03C443A5AFA05A6D9352FEF1212A5AF6|cdsA]-[gene|58CDF08A8F05C0BC25EB6E400316F85FD0F307E5|ispC]-[gene|CB50289535EA537F63BADD459BD11AA7759A6658|rasP]-[gene|848570563D3C92A8E1E6AB4DA530388D8AE94E75|proS]-[gene|FB97DF0C147FB29944F60214CB9BC1803861DAA0|polC]
    description
    [Pubmed|22383849]
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    additional information

  • the mRNA is very stable (> 15 min) [pubmed|12884008]

    • References

  • 12884008,15743965,19820159,24968740