SubtiBank SubtiBank
kipR
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kipR

transcriptional repressor of the kip operon
Locus
BSU_04100
Isoelectric point
5.43
Molecular weight
27.16 kDa
Protein length
250 aa Sequence Blast
Gene length
753 bp Sequence Blast
Function
regulation of sporulation initiation
Product
transcriptional regulator
Essential
no
Synonyms
ycsO

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
461,615 462,367

The protein

Domains

  • HTH iclR-type domain (aa 5-65) (according to UniProt)
  • IclR-ED (aa 80-249) (according to UniProt)
  • Structure

  • 1MKM (from Thermotoga maritima, 33% identity) PubMed
  • Expression and Regulation

    Operons

    Description

    Regulatory mechanism

  • KipR: repression, PubMed, in KipR regulon
  • TnrA: activation, PubMed, in TnrA regulon
  • Regulation

  • induced in the presence of 5-oxoproline PubMed
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    Biological materials

    Mutant

  • BKE04100 (kipR::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_ATTCTGCATCATTCATCCCC, downstream forward: _UP4_TAAGTAGCCAATCTTTTCTC
  • BKK04100 (kipR::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_ATTCTGCATCATTCATCCCC, downstream forward: _UP4_TAAGTAGCCAATCTTTTCTC
  • References

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