ywbH [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

holin-like protein

locus: BSU38320

pI: 9.00

mw: 14.00 kDa

function: unknown

product: holin-like protein

essential: no

synonyms: ipa-23r, cidA

Genomic Context

categories

• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

[SW|Categories] containing this gene/protein

• [SW|membrane proteins], [SW|proteins of unknown function]

Gene

Coordinates on the chromosome (coding sequence): 3,933,209 -> 3,933,595

Phenotypes of a mutant

• a ''[SW|ywbH]-[SW|ywbG]'' mutant is delayed in pellicle formation [Pubmed|26060272]
• a ''[SW|ywbH]-[SW|ywbG] [SW|yxaK]-[SW|yxaC] [SW|ysbA]-[SW|ysbB]'' triple mutant is severely delayed in pellicle formation [Pubmed|26060272]
• a ''[SW|ywbH]-[SW|ywbG]'' overexpression strain has more robust pellicle formation [Pubmed|26060272]

The protein

Protein family

• CidA subfamily (according to Swiss-Prot)

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|ywbH]-[protein|search|ywbG]'' [Pubmed|22383849]

Regulation

• induced by acetate ([protein|search|YwbI]) [Pubmed|26060272]

Regulatory mechanism

• [protein|search|YwbI]: transcription activation [Pubmed|26060272]

References

• 26060272,15659658,17452642