N-acetylglucosamine-specific phosphotransferase system, EIICB of the PTS
function
N-acetylglucosamine uptake and phosphorylation
product
N-acetylglucosamine-specific PTS, EIICB
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.2|Phosphotransferase system] → [category|SW 1.2.2.2|Sugar specific PTS proteins][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.17|Utilization of amino sugars][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.3|Utilization of amino sugars][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.3|Phosphorylation on a Cys residue][SW|Categories] containing this gene/protein
[SW|phosphotransferase systems], [SW|utilization of specific carbon sources], [SW|membrane proteins], [SW|phosphoproteins]This gene is a member of the following [SW|regulons]
[SW|NagR regulon]Gene
Coordinates on the chromosome (coding sequence)
840,656 -> 842,014
Phenotypes of a mutant
no growth on N-acetylglucosamine [Pubmed|23667565]The protein
Catalyzed reaction/ biological activity
Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)Protein family
[SW|PTS] permease, glucose permease (Glc) family [Pubmed|10627040]Paralogous protein(s)
[protein|search|GamP][SW|Localization]
cell membrane (according to Swiss-Prot), membrane associated [Pubmed|18763711]Expression and Regulation
Operon
''[protein|search|nagP]'' [Pubmed|23667565][SW|Sigma factor]
[protein|search|SigA] [Pubmed|23667565]Regulation
induced in the presence of N-acetylglucosamine ([protein|search|NagR]) [Pubmed|21602348]Regulatory mechanism
[protein|search|NagR]: transcription repression [Pubmed|21602348]References
Reviews
Original publications
10627040,18763711,10627040,6174502,23667565,21602348,23876412 
