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topB [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]
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topB [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

DNA topoisomerase III
locus
BSU04260
pI
9.00
mw
81.00 kDa
function
replication
product
DNA topoisomerase III
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.3|DNA condensation/ segregation]

    • [SW|Categories] containing this gene/protein

  • [SW|DNA replication], [SW|DNA condensation/ segregation]

    • Gene

    Coordinates on the chromosome (coding sequence)
    476,558 -> 478,741

    The protein

    Catalyzed reaction/ biological activity

  • ATP-independent breakage of single-stranded DNA, followed by passage and rejoining (according to Swiss-Prot)

    • Protein family

  • prokaryotic type I/III topoisomerase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|search|TopA]

    • [SW|Domains]

  • N-terminal [SW|TOPRIM domain] (aa 3-136) [Pubmed|9722641]

    • Structure

  • [PDB|2GAI] (from ''Thermotoga maritima'', 26% identity) [Pubmed|16600296]

    • Biological materials

    Mutant

  • BKE04260 (''topB''::''ermC'') (available at the [http://www.bgsc.org/ BGSC] and in [SW|Jörg Stülke]'s lab)
  • GP1864 (''topB''::''ermC'') (available in [SW|Jörg Stülke]'s lab)
  • GP1896 (''topB''::''cat'') (available in [SW|Jörg Stülke]'s lab)

    • References

  • 17114254,16600296,9722641