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dacA [Tue Feb 23 2016 19:10:45 GMT+0100 (CET)]
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dacA [Tue Feb 23 2016 19:10:45 GMT+0100 (CET)]

penicillin-binding protein 5, major D-alanyl-D-alanine carboxypeptidase
locus
BSU00100
pI
5.00
mw
48.00 kDa
function
carboxypeptidase
product
penicillin-binding protein 5,
D-alanyl-D-alanine carboxypeptidase
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.7|Penicillin-binding proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • [SW|Categories] containing this gene/protein

  • [SW|cell wall synthesis], [SW|membrane proteins], [SW|penicillin-binding proteins]

    • Gene

    Coordinates on the chromosome (coding sequence)
    17,534 -> 18,865

    The protein

    Catalyzed reaction/ biological activity

  • Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala (according to Swiss-Prot)

    • Protein family

  • peptidase S11 family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|search|DacF]

    • [SW|Localization]

  • secreted (according to Swiss-Prot), membrane associated [Pubmed|18763711]

    • Biological materials

    Mutant

  • 1A742 ( ''dacA''::''cat''), [Pubmed|3087956], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A742&Search=1A742 BGSC]
  • 1A743 ( ''dacA''::''cat''), [Pubmed|3087956], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A743&Search=1A743 BGSC]

    • References

  • 9864321,18763711,14731276,10383963,23531131,23199363,26499795